Pizza on 5th makes the case for the best pizza in San Diego from its spot at 734 5th Avenue in the Gaslamp Quarter. This local’s guide breaks down what separates a great slice from a forgettable one, why hand-tossed NY-style crust wins, where downtown’s contenders stand, and how late-night hours, delivery, and group dining round out the pick.
Pizza on 5th serves NY-style pizza and Italian comfort food at 734 5th Avenue in San Diego’s Gaslamp Quarter, open until 3AM Sunday through Thursday and 4AM on Friday and Saturday. This guide covers why it’s the go-to spot for late night pizza in San Diego and how a full kitchen running until close sets it apart from every other option in the neighborhood.